Sertraline: 7 things you should know

Sertraline , sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor SSRI class. Common side effects include diarrhea , sexual dysfunction , and troubles with sleep. Sertraline was approved for medical use in the United States in and initially sold by Pfizer. It is unclear if sertraline is any different from another SSRI, paroxetine , for depression; though escitalopram may have some benefits over sertraline. Evidence does not show a benefit in children with depression. With depression in dementia, there is no benefit compared to either placebo or mirtazapine. Tricyclic antidepressants TCAs as a group are considered to work better than SSRIs for melancholic depression [20] and in inpatients, [21] but not necessarily for simply more severe depression. A review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD.

19 men share what it’s like to take antidepressants

Skip to content. More and more women are taking antidepressants—particularly selective serotonin reuptake inhibitors SSRIs —during pregnancy, and many in the field consider this safe. However, some studies, including a new paper published in JAMA Pediatrics by researchers at Columbia University Vagelos College of Physicians and Surgeons, suggest that SSRIs may affect emotional learning, potentially raising the risk of depression later during puberty.

What does the latest research say about the effect of prenatal antidepressant exposure on children?

Would you date someone that tells you they have been on Zoloft for 3 years? 12 Answers. Jack J Wu, M.D. from Duke University School of Medicine ().

When it comes to mental health, everyone deals with things differently — which means that different treatments work for different people. While some people get by with self-care and coping mechanisms, others benefit from therapy, psychiatry, and medication. Duncan was first prescribed antidepressants in , after being diagnosed and prescribed them by his GP. The side effects varied depending on when I took the medication. This should stand me in good stead when I come off them.

Antidepressants, if appropriate, or other medication depending on the illness. I also went through counselling from January to September which was very beneficial. Adam was first prescribed antidepressants last September by his GP. Adam was prescribed Fluoxetine, which made him experience a number of side effects including tiredness, weight loss, and night sweats. My original diagnosis was from my GP and have seen a couple of psychiatrists since then as well as regular visits to a GP.


A cute guy can become a panic attack trigger, leaving me to flee mid-date to avoid a public meltdown. Almost immediately, though, I stopped having panic attacks in situations that would normally make me uncomfortable. Soon after that, I met Dan not his real name online. I found him incredibly attractive, funny, and engaging.

I thought he was perfect for me, and we transitioned from dating to a relationship with no panic attacks. Sleeping over or meeting his friends would have previously led to extreme anxiety, but it felt, for the first time in my life, easy.

perforatum) has a history of use as a medicine dating back to ancient Greece, where For example, in the same study, Zoloft also failed to show any benefit in​.

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What I Want You To Know About Dating With OCD And Intrusive Thoughts

To evaluate whether antidepressants alter expression of psychopathic personality traits in patients with major depressive disorder MDD. Change in PPI scores were assessed using paired t-tests for all subjects who completed a baseline and post-randomization PPI. Ninety patients 84 completers and 6 who terminated the trial early were eligible for the analysis. Both PPI factors changed significantly from baseline to endpoint, but in opposing directions. The mean score on PPI-1 increased significantly during treatment; this change was weakly correlated with change in depression scores.

As a new Zoloft user and 26 year old single male, I’m curious what people’s dating experiences have been on Zoloft. From my short experience, the .

Have you ever felt like your antidepressant has killed more than just your ability to orgasm? Like it’s killed all your feelings of love for your partner as well? SSRIs work by raising your levels of serotonin, but they can also decrease dopamine transmission. Dopamine is the neurotransmitter responsible for many of those feel-good emotions you get when you fall in love.

This effect, sometimes called emotional blunting , can also include such symptoms as feeling less empathetic, less able to cry, and less able to experience the same degree of positive emotion as one normally would. SSRI antidepressants are sometimes associated with something called emotional blunting. This can also include such symptoms as feeling indifferent or apathetic, being less able to cry and less able to experience the same degree of positive emotion as one normally would.

Emotional blunting may also be connected to sexual side effects, such as decreased libido and difficulty with orgasm. Unfortunately for people in romantic relationships, a loss of sexual desire coupled with a decreased ability to feel strong emotions can leave them feeling less in love.


The discourse around mental health has picked up speed, but it remains an underserved topic. Imperceptible rejections could propel week-long crying jags , gentle self-harmings digging my nails into my palms, slamming my head into the side of a bathroom stall felt better than living inside my brain. One thought became eight thoughts became an endless, tangled river of possibilities, inadequacies, shortcomings, failures.

In bad times, I would go weeks without eating a real meal, feeding myself on the crumbs of my dramas and the odd croissant. Despite this, I believed myself to be generally fine.

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The violent thoughts came to me suddenly, and without hesitation, in the summer of June It was 5pm, and I was lounging around the beach house with my parents, when all at once, I was hit with a wave of the loudest and most disturbing thoughts I have ever had. I remember trying to distract myself by taking a shower, but the hot water running down my body did nothing to soothe my mind. After that day, no matter what I did, or where I went, disturbing thoughts followed me like a ghost.

I was powerless to them. My intrusive thoughts were extremely violent and unforgiving. For the rest of that summer I retreated to my bed in my lonely apartment, trying to sleep away the days, convinced I would never be normal again. Days turned into weeks that turned into months and I was nowhere near to being fine. Each day I woke up, praying that these disturbing thoughts could magically go away.

That perhaps, I could send them off with the right amount of sunshine, and Himalayan salt lamps. And sunshine can only do so much for a mental illness.

The Effects of Sertraline on Psychopathic Traits

Study record managers: refer to the Data Element Definitions if submitting registration or results information. Obsessive-compulsive disorder OCD is an anxiety disorder that is associated with recurring repetitive behaviors and persistent unwanted thoughts. People with OCD often carry out ritual-like behaviors such as counting, cleaning, or washing their hands in order to momentarily ease their anxiety.

Of an extremely rare in my brain. O. Both men appetence slow dating prozac, zoloft sertraline. Zoloft, zoloft is taken my sex drive. Sertraline. Antidepressant that​.

She then began taking antidepressant medication. Her libido nosedived. She began struggling to orgasm, and sex with her husband of 10 years dwindled to one encounter every few months. Peter, in his late 20s, started taking an antidepressant several months ago and immediately experienced a loss of libido and sex drive, as well as difficulty in reaching orgasm.

About 10 per cent of Australians currently take antidepressants. Those medications are literally lifesavers for many individuals, but some have side effects that include a lowered desire for sex; difficulty becoming or staying aroused; or problems related to orgasm, including delayed ejaculation. So how can you take back your sex life if medication is dulling your drive? Here are some suggestions experts say are worth investigating. It can take up to several weeks for antidepressants to work optimally and for acute side effects to pass.

Keep in mind it can be difficult to tell whether antidepressants are causing your sexual problems. Other factors such as alcohol, other medications, stress, anxiety, or overthinking the issue can also be culprits. She recommends having an open dialogue with your GP about which of these factors might be causing sexual dysfunction, so you and your doctor can properly weigh the drug’s therapeutic benefits against any side effects.

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Zoloft (sertraline): An Overview of Depression and Clinical Uses for Sertraline